Prenatal Triclosan Exposure and Anthropometric Measures Including Anogenital Distance in Danish Infants
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چکیده
منابع مشابه
Prenatal Triclosan Exposure and Anthropometric Measures Including Anogenital Distance in Danish Infants
BACKGROUND Triclosan (TCS) is widely used as an antibacterial agent in consumer products such as hand soap and toothpaste, and human exposure is widespread. TCS is suspected of having endocrine-disrupting properties, but few human studies have examined the developmental effects of prenatal TCS exposure. OBJECTIVES We prospectively examined associations between prenatal TCS exposure and anthro...
متن کاملPrenatal Exposure to Phthalates and Anogenital Distance in Male Infants from a Low-Exposed Danish Cohort (2010–2012)
BACKGROUND Phthalates comprise a large class of chemicals used in a variety of consumer products. Several have anti-androgenic properties, and in rodents prenatal exposure has been associated with reduced anogenital distance (AGD)-the distance from the anus to the genitals in male offspring. Few human studies have been conducted, but associations between the anti-androgenic phthalates and male ...
متن کاملDecrease in Anogenital Distance among Male Infants with Prenatal Phthalate Exposure
Prenatal phthalate exposure impairs testicular function and shortens anogenital distance (AGD) in male rodents. We present data from the first study to examine AGD and other genital measurements in relation to prenatal phthalate exposure in humans. A standardized measure of AGD was obtained in 134 boys 2-36 months of age. AGD was significantly correlated with penile volume (R = 0.27, p = 0.001)...
متن کاملPrenatal paracetamol exposure is associated with shorter anogenital distance in male infants
STUDY QUESTION What is the relationship between maternal paracetamol intake during the masculinisation programming window (MPW, 8-14 weeks of gestation) and male infant anogenital distance (AGD), a biomarker for androgen action during the MPW? SUMMARY ANSWER Intrauterine paracetamol exposure during 8-14 weeks of gestation is associated with shorter AGD from birth to 24 months of age. WHAT I...
متن کاملIn Utero Exposure to Dioxins and Dioxin-like Compounds and Anogenital Distance in Newborns and Infants
BACKGROUND Anogenital distance in animals is used as a measure of fetal androgen action. Prenatal exposure to dioxins and dioxin-like compounds in rodents causes reproductive changes in male offspring and decreases anogenital distance. OBJECTIVE We assessed whether in utero exposure to dioxins and dioxin-like compounds adversely influences anogenital distance in newborns and young children (m...
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ژورنال
عنوان ژورنال: Environmental Health Perspectives
سال: 2016
ISSN: 0091-6765,1552-9924
DOI: 10.1289/ehp.1409637